Police are appealing for witnesses after a motorcycle crashed following a short pursuit in Tweed Heads overnight.

About 12.15am Tweed Heads police in an unmarked vehicle attempted to stop a Suzuki GSX1400 motorcycle after it was allegedly detected speeding on Sexton Hill, Tweed Heads.

It will be alleged it failed to stop and a pursuit was initiated, coming to an end when the motorcycle failed to negotiate a moderate right-hand bend on Tweed Coast Road, Chinderah.

Police rendered first aid until the arrival of paramedics, with the rider being taken to Tweed Heads Hospital with fractured ribs, a punctured lung and lacerations.

The 40-year-old man, from Kingscliff, remains in hospital in a stable condition.

Police from Tweed/Byron Local Area Command attended the scene, with ongoing inquiries being carried out by officers from the Ballina Crash Investigation Unit.

Police are appealing for witnesses to the crash, or the moments leading up to it, to contact Ballina Crash Investigation Unit on (02) 6681 8618 or Crime Stoppers on 1800 333 000.