Specialist Rescue and Bomb Disposal Squad officers will today examine the scene of an explosion, in which a North Coast teenager lost his hand.

Emergency services personnel responded to reports of an explosion in a bedroom of a house on Riverside Drive at Seelands, near Grafton, about 5.15pm yesterday (Friday 30 April).

Upon arrival, they found a 16-year-old boy who had lost one hand in the blast and had severely injured the other. He had also sustained shrapnel wounds.

The teenager was taken by NSW Ambulance Paramedics to Grafton Hospital for treatment before being transferred to Coffs Harbour Base Hospital.

The explosion caused significant damage to the room and its contents.

Police from Coffs/Clarence Local Area Command sought advice from Sydney-based Rescue and Bomb Disposal Squad officers before establishing a perimeter around the scene.

The scene has been secured overnight with RBDS officers expected to arrive in Seelands later today.

Investigations into the circumstances surrounding the incident are continuing and police hope to speak with the boy once his condition allows.